Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 9/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.69 |
| ▸ | POLB | P06746 | 4/20 | 0.69 |
| ▸ | RECQL | P46063 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | APEX1 | P27695 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | MMP1 | P03956 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | BLM | P54132 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.59 |
| ▸ | PLG | P00747 | 1/20 | 0.59 |
| ▸ | SRC | P12931 | 2/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.58 |
| ▸ | TUBB | P07437 | 1/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28067122 | 0.86 | POLH (0.76) | POLHKDM4EPOLBRECQLMEN1 | |
| SCHEMBL28229331 | 0.84 | POLH (0.72) | POLHKDM4EPOLBRECQLMEN1 | |
| SCHEMBL7202826 | 0.84 | POLH (1.00) | POLHKDM4EPOLBRECQLMEN1 | |
| SCHEMBL17102291 | 0.82 | POLH (0.82) | POLHKDM4EPOLBRECQLMEN1 | |
| 3-O-Methylquercetin SCHEMBL380558 | 0.82 | POLH (1.00) | POLHKDM4EPOLBRECQLMEN1 | |
| 3-O-Methylquercetin SCHEMBL29897544 | 0.82 | POLH (1.00) | POLHKDM4EPOLBRECQLMEN1 | |
| SCHEMBL17620378 | 0.82 | POLH (0.89) | POLHKDM4EPOLBRECQLMEN1 | |
| SCHEMBL10728956 | 0.82 | POLH (1.00) | POLHKDM4EPOLBRECQLMEN1 | |
| SCHEMBL7914456 | 0.82 | POLH (0.79) | POLHKDM4EPOLBRECQLMEN1 | |
| SCHEMBL23440446 | 0.81 | POLH (0.68) | POLHKDM4EPOLBRECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060229358-A1 | Pharmaceutical composition containing flavonoids | TAIPEI MEDICAL UNIVERSITY (TW) | 2006-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229358-A1 | Pharmaceutical composition containing flavonoids | PDE4B, PDE4A, PDE3B | POLH 4046/4885KDM4E 1018/4885POLB 3129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.