Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 3/20 | 0.33 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | NOS2 | P35228 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593076 | 0.90 | ALDH1A1 (0.35) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL13576631 | 0.90 | ALDH1A1 (0.35) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL4619843 | 0.87 | ALDH1A1 (0.34) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL11814389 | 0.84 | NOS3 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL11072795 | 0.83 | — | — | |
| SCHEMBL7627448 | 0.80 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL31406995 | 0.77 | KDM4E (0.32) | — | |
| SCHEMBL17913112 | 0.77 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL11348181 | 0.77 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL15467099 | 0.75 | ALDH1A1 (0.32) | ALDH1A1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615866-A1 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | Inflazyme Pharmaceuticals, Ltd. (CA) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004092100-A1 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | INFLAZYME PHARMACEUTICALS LTD. (CA) | 2004-10-28 | — | — | WO | disclosed |