Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13576631 | 1.00 | ALDH1A1 (0.35) | ALDH1A1NOS1NOS2NOS3 | |
| SCHEMBL11814389 | 0.95 | NOS3 (0.33) | NOS1NOS2NOS3 | |
| SCHEMBL4619843 | 0.92 | ALDH1A1 (0.34) | ALDH1A1NOS1NOS2NOS3 | |
| SCHEMBL6014090 | 0.90 | ALDH1A1 (0.35) | ALDH1A1NOS1NOS2NOS3 | |
| SCHEMBL7627448 | 0.85 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL11348181 | 0.81 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL17913112 | 0.81 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL31406995 | 0.77 | KDM4E (0.32) | — | |
| SCHEMBL14401351 | 0.77 | — | — | |
| SCHEMBL28506582 | 0.73 | NOS1 (0.32) | ALDH1A1NOS1NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029723-B | Composition flexible with enhancing | 莫门蒂夫性能材料股份有限公司 | 2019-07-09 | — | — | CN | claimed |
| CN-106029723-A | Compositions with enhanced flexibility | 莫门蒂夫性能材料股份有限公司 | 2016-10-12 | — | — | CN | claimed |
| EP-1230227-B1 | BENZOXA-AND BENZOTHIAZOLYL SULFAMATES AND THEIR USE AS STEROID SULFATASE INHIBITORS | NOVARTIS AG (CH) | 2004-06-23 | — | — | EP | claimed |
| CN-106488900-A | Prins reaction on hindered substrates | 弗门尼舍有限公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-106029723-A | Compositions with enhanced flexibility | 莫门蒂夫性能材料股份有限公司 | 2016-10-12 | — | — | CN | disclosed |
| EP-1230227-B1 | BENZOXA-AND BENZOTHIAZOLYL SULFAMATES AND THEIR USE AS STEROID SULFATASE INHIBITORS | NOVARTIS AG (CH) | 2004-06-23 | — | — | EP | disclosed |
| US-6716865-B1 | SUBSTITUTED AT THE 2 POSITION; A SULFAMATE BOUND VIA OXYGEN TO THE PHENYL PART OF THE RING STRUCTURE; SULFAMOYLATION; STEROID SULFATASE INHIBITOR, ACNE | NOVARTIS AG (CH) | 2004-04-06 | — | — | US | disclosed |
| EP-1230227-A1 | BENZOXA-AND BENZOTHIAZOLYL SULFAMATES AND THEIR USE AS STEROID SULFATASE INHIBITORS | Novartis AG (CH) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036398-A1 | BENZOXA- AND BENZTHIAZOLES | NOVARTIS AG (CH) | 2001-05-25 | — | — | WO | disclosed |
| US-3971804-A | ACARICIDES, FUNGICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-27 | — | — | US | disclosed |