Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 3/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014282 | 0.90 | RAB9A (0.41) | HPGDRAB9AHTTNPC1CYP1A2 | |
| SCHEMBL6014256 | 0.88 | LMNA (0.43) | HPGDRAB9AHTTNPC1CYP1A2 | |
| SCHEMBL6014277 | 0.87 | LMNA (0.42) | HPGDRAB9AHTTNPC1CYP3A4 | |
| SCHEMBL6014281 | 0.87 | LMNA (0.42) | HPGDRAB9AHTTNPC1CYP1A2 | |
| SCHEMBL6014231 | 0.86 | LMNA (0.42) | HPGDRAB9AHTTNPC1ALDH1A1 | |
| SCHEMBL6014228 | 0.86 | LMNA (0.42) | HPGDHTTNPC1ALDH1A1ALOX15 | |
| SCHEMBL6014312 | 0.86 | TSHR (0.44) | HPGDRAB9AHTTNPC1CYP1A2 | |
| SCHEMBL6014239 | 0.86 | LMNA (0.43) | HPGDNPC1ALDH1A1LMNAMAPK1 | |
| SCHEMBL6016093 | 0.85 | ALDH1A1 (0.45) | HPGDRAB9AHTTNPC1ALDH1A1 | |
| SCHEMBL6014250 | 0.84 | LMNA (0.41) | HPGDRAB9AHTTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006128268-A1 | UREIDIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE ON THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ (BR) | 2006-12-07 | — | — | WO | claimed |