Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014291 | 1.00 | LMNA (0.42) | LMNATDP1ALDH1A1KDM4ENPC1 | |
| SCHEMBL6014315 | 0.99 | LMNA (0.43) | LMNATDP1ALDH1A1KDM4ENPC1 | |
| SCHEMBL6014276 | 0.95 | LMNA (0.44) | LMNATDP1ALDH1A1KDM4ENPC1 | |
| SCHEMBL6014232 | 0.89 | KDM4E (0.41) | TDP1ALDH1A1KDM4ENPC1HSD17B10 | |
| SCHEMBL6014285 | 0.85 | TRPM8 (0.39) | ALDH1A1KDM4ENPC1SMN1; SMN2TSHR | |
| SCHEMBL6014265 | 0.83 | LMNA (0.47) | LMNATDP1ALDH1A1KDM4ENPC1 | |
| SCHEMBL6014271 | 0.82 | LMNA (0.47) | LMNATDP1ALDH1A1KDM4ENPC1 | |
| SCHEMBL6014316 | 0.80 | LMNA (0.45) | LMNATDP1ALDH1A1KDM4ENPC1 | |
| SCHEMBL6014300 | 0.80 | LMNA (0.45) | LMNATDP1ALDH1A1KDM4ENPC1 | |
| SCHEMBL6014320 | 0.78 | LMNA (0.44) | LMNATDP1ALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006128268-A1 | UREIDIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE ON THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ (BR) | 2006-12-07 | — | — | WO | claimed |