Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014232 | 0.87 | KDM4E (0.41) | TRPM8NPC1RAB9AALDH1A1GAA | |
| SCHEMBL6014291 | 0.85 | LMNA (0.42) | TRPM8NPC1RAB9AALDH1A1GAA | |
| SCHEMBL6014284 | 0.85 | LMNA (0.42) | TRPM8NPC1RAB9AALDH1A1GAA | |
| SCHEMBL6014315 | 0.83 | LMNA (0.43) | TRPM8NPC1RAB9AALDH1A1GAA | |
| SCHEMBL6014276 | 0.79 | LMNA (0.44) | NPC1RAB9AALDH1A1GAAHPGD | |
| Urea SCHEMBL6014279 | 0.77 | L3MBTL1 (0.42) | NPC1RAB9AALDH1A1GAAHPGD | |
| SCHEMBL6014230 | 0.72 | NPC1 (0.39) | NPC1RAB9AALDH1A1GAAHPGD | |
| SCHEMBL6014238 | 0.72 | NPC1 (0.48) | TRPM8NPC1RAB9AALDH1A1GAA | |
| SCHEMBL6014278 | 0.70 | KMT2A (0.39) | NPC1RAB9AALDH1A1GAAHPGD | |
| SCHEMBL6014289 | 0.70 | TRPM8 (0.45) | TRPM8NPC1RAB9AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006128268-A1 | UREIDIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE ON THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ (BR) | 2006-12-07 | — | — | WO | claimed |
| WO-2006128268-A1 | UREIDIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE ON THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ (BR) | 2006-12-07 | — | — | WO | disclosed |