Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL6016094 | 0.83 | MGAM (0.47) | NPC1RAB9AHPGDSMN1; SMN2TP53 | |
| SCHEMBL5553780 | 0.82 | MGAM (0.51) | NPC1RAB9AHPGDSMN1; SMN2TP53 | |
| SCHEMBL6014238 | 0.81 | NPC1 (0.48) | NPC1RAB9AHPGDSMN1; SMN2HPGDS | |
| Hydrogen Sulfide SCHEMBL28775857 | 0.80 | MGAM (0.50) | NPC1RAB9AHPGDSMN1; SMN2TP53 | |
| SCHEMBL6014289 | 0.78 | TRPM8 (0.45) | NPC1RAB9AHPGDKMT2AALDH1A1 | |
| SCHEMBL6014252 | 0.78 | TRPM8 (0.45) | NPC1RAB9AHPGDKMT2AALDH1A1 | |
| SCHEMBL7508967 | 0.74 | NPC1 (0.62) | NPC1RAB9AHPGDSMN1; SMN2TP53 | |
| SCHEMBL6084961 | 0.74 | NPC1 (0.62) | NPC1RAB9AHPGDSMN1; SMN2TP53 | |
| SCHEMBL19020851 | 0.73 | MGAM (0.51) | NPC1RAB9AHPGDSMN1; SMN2TP53 | |
| SCHEMBL18987604 | 0.70 | HPGDS (0.69) | HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006128268-A1 | UREIDIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE ON THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ (BR) | 2006-12-07 | — | — | WO | claimed |
| WO-2006128268-A1 | UREIDIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE ON THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ (BR) | 2006-12-07 | — | — | WO | disclosed |