Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ITK | Q08881 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014289 | 1.00 | TRPM8 (0.45) | TRPM8NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6014238 | 0.87 | NPC1 (0.48) | TRPM8NPC1RAB9AMEN1KMT2A | |
| Urea SCHEMBL6016094 | 0.79 | MGAM (0.47) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL6014290 | 0.78 | NPC1 (0.46) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5553780 | 0.78 | MGAM (0.51) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| Hydrogen Sulfide SCHEMBL28775857 | 0.76 | MGAM (0.50) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL19020851 | 0.70 | MGAM (0.51) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL6014285 | 0.70 | TRPM8 (0.39) | TRPM8NPC1RAB9AMEN1KMT2A | |
| SCHEMBL967449 | 0.69 | L3MBTL1 (0.49) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL27367583 | 0.68 | L3MBTL1 (0.47) | NPC1RAB9AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006128268-A1 | UREIDIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE ON THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ (BR) | 2006-12-07 | — | — | WO | claimed |
| WO-2006128268-A1 | UREIDIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE ON THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ (BR) | 2006-12-07 | — | — | WO | disclosed |