Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014239 | 0.89 | LMNA (0.43) | ALDH1A1MAPTTSHRNPC1TP53 | |
| SCHEMBL6014242 | 0.86 | ALDH1A1 (0.46) | EDNRAALDH1A1MAPTTSHRNPC1 | |
| SCHEMBL6014245 | 0.85 | TRPM8 (0.40) | EDNRAALDH1A1MAPTTSHRNPC1 | |
| SCHEMBL6014277 | 0.83 | LMNA (0.42) | ALDH1A1MAPTTSHRNPC1TP53 | |
| SCHEMBL6014256 | 0.82 | LMNA (0.43) | ALDH1A1MAPTTSHRNPC1TP53 | |
| SCHEMBL6014250 | 0.80 | LMNA (0.41) | ALDH1A1MAPTTSHRNPC1TP53 | |
| SCHEMBL6014312 | 0.80 | TSHR (0.44) | ALDH1A1MAPTTSHRNPC1TP53 | |
| SCHEMBL6014228 | 0.80 | LMNA (0.42) | ALDH1A1MAPTTSHRNPC1TP53 | |
| SCHEMBL6014241 | 0.80 | HTT (0.43) | ALDH1A1MAPTTSHRNPC1ATM | |
| SCHEMBL6016093 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPTTSHRNPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006128268-A1 | UREIDIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE ON THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ (BR) | 2006-12-07 | — | — | WO | claimed |