Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31480992 | 0.91 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1SLC6A4SLC6A2POLB | |
| SCHEMBL16423362 | 0.82 | HDAC1 (0.39) | ALDH1A1L3MBTL1POLBLMNA | |
| SCHEMBL8351027 | 0.79 | SLC6A4 (0.41) | L3MBTL1SLC6A4SLC6A2SLC6A3PRKAB2 | |
| SCHEMBL17080542 | 0.79 | SLC6A4 (0.41) | SLC6A4SLC6A2SLC6A3DPP4PRKAB2 | |
| SCHEMBL2321615 | 0.79 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1SLC6A4SLC6A2POLB | |
| SCHEMBL2129 | 0.79 | SLC6A4 (0.58) | ALDH1A1SLC6A4SLC6A2SLC6A3PRKAB2 | |
| SCHEMBL7333210 | 0.78 | DPP4 (0.57) | ALDH1A1L3MBTL1SLC6A4SLC6A2POLB | |
| SCHEMBL5645600 | 0.77 | HSD11B1 (0.46) | ALDH1A1L3MBTL1SLC6A4SLC6A2POLB | |
| SCHEMBL10577936 | 0.77 | DPP4 (0.67) | ALDH1A1L3MBTL1SLC6A4SLC6A2SLC6A3 | |
| Ammonia Solution, Strong SCHEMBL7260918 | 0.77 | DPP4 (0.55) | ALDH1A1L3MBTL1SLC6A4SLC6A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633712-B1 | SIX MEMBERED AMINO-AMIDE DERIVATIVES AS ANGIOGENESIS INHIBITORS | CHEN GUOQING PAUL (US) | 2014-06-25 | — | — | EP | disclosed |
| US-7129252-B2 | Six membered amino-amide derivatives an angiogenisis inhibitors | HLB CO., LTD. (KR) | 2006-10-31 | — | — | US | disclosed |
| EP-1633712-A2 | SIX MEMBERED AMINO-AMIDE DERIVATIVES AS ANGIOGENESIS INHIBITORS | Chen, Guoqing Paul (US) | 2006-03-15 | — | — | EP | disclosed |
| WO-2005000232-A2 | SIX MEMBERED AMINO-AMIDE DERIVATIVES AS ANGIOGENESIS INHIBITORS | CHEN GUOQING PAUL (US) | 2005-01-06 | — | — | WO | disclosed |
| US-20040259916-A1 | Six membered amino-amide derivatives an angiogenisis inhibitors | HLB CO., LTD. (KR) | 2004-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259916-A1 | Six membered amino-amide derivatives an angiogenisis inhibitors | TEK, FLT1, VEGFA | ALDH1A1 3087/4885L3MBTL1 3679/4885SLC6A4 1529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.