Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014515 | 0.91 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1LMNAPOLBSLC6A4 | |
| SCHEMBL16423362 | 0.86 | HDAC1 (0.39) | ALDH1A1L3MBTL1LMNAPOLBALOX15 | |
| SCHEMBL7055234 | 0.79 | ESR2 (0.48) | ALDH1A1LMNAMAOAMAOBTAAR1 | |
| SCHEMBL8353941 | 0.77 | L3MBTL1 (0.41) | ALDH1A1L3MBTL1LMNAMAOAMAOB | |
| SCHEMBL3615305 | 0.77 | SLC6A4 (0.52) | ALDH1A1MAOAMAOBSLC6A4SLC6A2 | |
| SCHEMBL14710296 | 0.77 | SLC6A4 (0.37) | MAOAMAOBTAAR1SLC6A4SLC6A2 | |
| SCHEMBL7704791 | 0.77 | SLC6A3 (0.52) | MAOAMAOBSLC6A4SLC6A2PRKAB2 | |
| SCHEMBL5645623 | 0.77 | SLC6A2 (0.37) | MAOAMAOBTAAR1SLC6A4SLC6A2 | |
| SCHEMBL4275 | 0.77 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1LMNAMAOAMAOB | |
| SCHEMBL14176143 | 0.77 | CYP19A1 (0.46) | ALDH1A1L3MBTL1LMNAMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054339-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS INHIBITORS OF KIT | ARCUS BIOSCIENCES, INC. (US) | 2025-03-13 | — | — | WO | disclosed |