Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGFBP3 | P17936 | 20/20 | 1.00 |
| ▸ | IGFBP1 | P08833 | 1/20 | 1.00 |
| ▸ | IGFBP2 | P18065 | 1/20 | 1.00 |
| ▸ | IGFBP4 | P22692 | 1/20 | 1.00 |
| ▸ | IGFBP6 | P24592 | 1/20 | 1.00 |
| ▸ | IGFBP5 | P24593 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29930436 | 1.00 | IGFBP3 (1.00) | IGFBP3IGFBP1IGFBP2IGFBP4IGFBP6 | |
| Water SCHEMBL31319504 | 0.99 | IGFBP3 (0.97) | IGFBP3IGFBP1IGFBP2IGFBP4IGFBP6 | |
| SCHEMBL1758192 | 0.69 | CA12 (0.68) | IGFBP3IGFBP1IGFBP2IGFBP4IGFBP6 | |
| Protocatechuic Acid SCHEMBL27815804 | 0.67 | CA12 (1.00) | — | |
| Protocatechuic Acid SCHEMBL30030432 | 0.67 | CA12 (1.00) | — | |
| Protocatechuic Acid SCHEMBL39435 | 0.67 | CA12 (1.00) | — | |
| Protocatechuic Acid SCHEMBL29350008 | 0.67 | CA12 (1.00) | — | |
| Protocatechuic Acid SCHEMBL23495982 | 0.65 | CA12 (0.95) | — | |
| Protocatechuic Acid SCHEMBL2274950 | 0.65 | CA12 (0.95) | — | |
| Protocatechuic Acid SCHEMBL9491440 | 0.65 | CA12 (0.95) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276394-A1 | METHODS AND COMPOSITIONS FOR TREATING NEUROLOGICAL DISORDERS | WYETH (US) | 2006-12-07 | — | — | US | claimed |
| EP-3025714-B9 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML) | BIOGEN MA INC (US) | 2020-11-18 | — | — | EP | disclosed |
| EP-3025714-B1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML) | BIOGEN MA INC (US) | 2020-07-15 | — | — | EP | disclosed |
| EP-3025714-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML) | Biogen MA Inc. (US) | 2016-06-01 | — | — | EP | disclosed |