Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 15/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3450298 | 0.90 | CCR1 (0.41) | CCR1KMT2ALMNA | |
| SCHEMBL6015098 | 0.89 | ITGB3 (0.35) | CCR1 | |
| SCHEMBL6014965 | 0.88 | CCR1 (0.39) | CCR1 | |
| SCHEMBL3448413 | 0.88 | CCR1 (0.32) | CCR1KMT2A | |
| SCHEMBL3448280 | 0.86 | KMT2A (0.46) | CCR1CYP3A4CYP2C19KMT2ALMNA | |
| SCHEMBL6015029 | 0.85 | CCR1 (0.40) | CCR1CYP3A4KMT2A | |
| SCHEMBL6015112 | 0.84 | CCR1 (0.38) | CCR1LMNA | |
| SCHEMBL6014945 | 0.84 | ENPP2 (0.38) | CCR1 | |
| SCHEMBL3451234 | 0.84 | CCR1 (0.36) | CCR1 | |
| SCHEMBL3449084 | 0.83 | CCR1 (0.54) | CCR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695961-A1 | UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2006-08-30 | — | — | EP | disclosed |