Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | CTSL | P07711 | 4/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015112 | 0.90 | CCR1 (0.38) | CCR1KDM4E | |
| SCHEMBL3447639 | 0.89 | MAPK1 (0.32) | CCR1CYP3A4CALCRLCCKBRKDM4E | |
| SCHEMBL6015073 | 0.88 | CCR1 (0.40) | CCR1CCKBR | |
| SCHEMBL6015098 | 0.87 | ITGB3 (0.35) | CCR1 | |
| SCHEMBL6015003 | 0.87 | CCKBR (0.40) | CCR1CCKBR | |
| SCHEMBL3449306 | 0.86 | TSHR (0.31) | CCR1KMT2A | |
| SCHEMBL3450145 | 0.86 | CALCRL (0.32) | CCR1CALCRLCACNA1BKMT2A | |
| SCHEMBL6015065 | 0.86 | ALDH1A1 (0.43) | CYP3A4CALCRLKDM4EALDH1A1HSD17B10 | |
| SCHEMBL3451041 | 0.86 | ALDH1A1 (0.43) | CYP3A4CALCRLKDM4EALDH1A1HSD17B10 | |
| SCHEMBL6015148 | 0.86 | UBE2N (0.41) | CCR1KDM4EALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695961-A1 | UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2006-08-30 | — | — | EP | disclosed |