Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 6/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | CTSV | O60911 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3448985 | 0.86 | AAK1 (0.36) | CHRM3ENPP2TP53CTSL | |
| SCHEMBL6014945 | 0.84 | ENPP2 (0.38) | CHRM3ENPP2CCR1TP53CTSK | |
| SCHEMBL3449607 | 0.84 | RAB9A (0.41) | CHRM3CCR1TP53EPHX2 | |
| SCHEMBL3449091 | 0.83 | FPR2 (0.41) | CHRM3CCR1EPHX2 | |
| SCHEMBL3448661 | 0.82 | AAK1 (0.36) | CTSL | |
| SCHEMBL6015041 | 0.81 | CCR1 (0.38) | ENPP2CCR1 | |
| SCHEMBL6015058 | 0.81 | CCR1 (0.33) | CCR1 | |
| SCHEMBL3448700 | 0.79 | ENPP2 (0.33) | ENPP2 | |
| SCHEMBL3450745 | 0.79 | CCR1 (0.37) | CCR1CTSK | |
| SCHEMBL3451876 | 0.79 | CCR1 (0.39) | CHRM3CCR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695961-A1 | UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2006-08-30 | — | — | EP | disclosed |