Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2296670 | 0.85 | NR1I2 (0.47) | KDM4EALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL2296252 | 0.85 | NR1I2 (0.47) | KDM4EALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL2299633 | 0.85 | HTR1E (0.53) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5447209 | 0.85 | EPHX2 (0.48) | ALDH1A1MAPTHPGDSMN1; SMN2RAB9A | |
| SCHEMBL2294942 | 0.82 | HDAC3 (0.44) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5299923 | 0.82 | NR1I2 (0.44) | KDM4EALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL5298326 | 0.81 | RAB9A (0.47) | KDM4EALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL5294171 | 0.81 | RAB9A (0.46) | ALDH1A1MAPTHPGDSMN1; SMN2RAB9A | |
| SCHEMBL2296379 | 0.80 | NPC1 (0.46) | KDM4EALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL2295674 | 0.80 | NPC1 (0.56) | ALDH1A1MAPTHPGDSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060116383-A1 | Integrin antagonists useful as anticancer agents | ALCATEL LUCENT (FR) | 2006-06-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116383-A1 | Integrin antagonists useful as anticancer agents | ITGB5, ITGA5, ITGB1 | KDM4E 1654/4885ALDH1A1 1381/4885MAPT 4745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.