Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015135 | 0.93 | ALDH1A1 (0.46) | F10SMN1; SMN2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL3450361 | 0.89 | HRH2 (0.49) | F10KMT2AHRH2HRH1 | |
| SCHEMBL3451657 | 0.87 | F10 (0.45) | F10CHRM1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3451958 | 0.85 | F10 (0.42) | F10CHRM1ALDH1A1MMP1MMP3 | |
| SCHEMBL3450371 | 0.82 | F10 (0.42) | F10CHRM1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6014981 | 0.81 | F10 (0.43) | F10KDM4EHSD17B10ALDH1A1KMT2A | |
| SCHEMBL3450519 | 0.81 | FPR2 (0.49) | F10CHRM1ALDH1A1MMP1MMP3 | |
| SCHEMBL3448772 | 0.81 | FPR2 (0.49) | F10CHRM1ALDH1A1MMP1MMP3 | |
| SCHEMBL6015040 | 0.79 | F10 (0.45) | F10KMT2AP2RY12 | |
| SCHEMBL3449377 | 0.79 | F10 (0.46) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695961-A1 | UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2006-08-30 | — | — | EP | disclosed |