Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015073 | 0.90 | CCR1 (0.40) | UBE2NCCR1 | |
| SCHEMBL6015003 | 0.88 | CCKBR (0.40) | CCR1 | |
| SCHEMBL6015112 | 0.88 | CCR1 (0.38) | KDM4ECCR1 | |
| SCHEMBL3450145 | 0.87 | CALCRL (0.32) | KMT2ATSHRCCR1 | |
| SCHEMBL3449985 | 0.86 | CCKBR (0.32) | CCR1 | |
| SCHEMBL6015029 | 0.86 | CCR1 (0.40) | KMT2AALDH1A1KDM4EMEN1HSD17B10 | |
| SCHEMBL3448501 | 0.85 | CCR1 (0.40) | UBE2NKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL3449253 | 0.85 | CCKBR (0.31) | CCR1 | |
| SCHEMBL3449306 | 0.84 | TSHR (0.31) | KMT2ATSHRCCR1 | |
| SCHEMBL3451041 | 0.83 | ALDH1A1 (0.43) | KMT2AALDH1A1KDM4EMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695961-A1 | UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2006-08-30 | — | — | EP | disclosed |