Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573652 | 0.74 | HPGD (0.39) | ALDH1A1HPGDRAB9A | |
| SCHEMBL29520731 | 0.67 | RECQL (0.38) | GAAHPGDRAB9A | |
| SCHEMBL3802279 | 0.65 | POLB (0.39) | LMNAGAAALDH1A1HPGD | |
| SCHEMBL27740306 | 0.64 | GPR3 (0.34) | GAAALDH1A1HPGD | |
| SCHEMBL19798248 | 0.64 | GPR3 (0.34) | GAAALDH1A1HPGD | |
| SCHEMBL27721238 | 0.64 | GPR3 (0.34) | LMNAGAAALDH1A1HPGD | |
| SCHEMBL28150127 | 0.64 | ELANE (0.35) | HIF1AALDH1A1 | |
| SCHEMBL12998307 | 0.64 | KDM4E (0.47) | GAAALDH1A1HPGD | |
| SCHEMBL14699098 | 0.64 | TSHR (0.41) | HIF1AALDH1A1HPGD | |
| SCHEMBL23937822 | 0.62 | ESR1 (0.36) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713779-A1 | INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE-SENSITIVE LIPASES | Sanofi-Aventis Deutschland GmbH (DE) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005073199-A1 | INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE-SENSITIVE LIPASES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2005-08-11 | — | — | WO | disclosed |