Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCPS | Q96C86 | 12/20 | 0.54 |
| ▸ | DHFR | P00374 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | INSR | P06213 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015544 | 0.94 | DCPS (0.57) | DCPSDHFRCYP2D6 | |
| SCHEMBL1154830 | 0.86 | DCPS (0.66) | DCPSDHFRCYP2D6 | |
| SCHEMBL6015543 | 0.81 | DCPS (0.80) | DCPSDHFRCYP2D6 | |
| SCHEMBL621583 | 0.79 | BRD4 (0.44) | DCPSDHFRF2F10PLG | |
| SCHEMBL6015547 | 0.77 | CHRNB2 (0.51) | DCPSDHFRF2PLGPLAU | |
| SCHEMBL6015539 | 0.77 | CHRNB2 (0.51) | DCPSDHFRF2PLGPLAU | |
| SCHEMBL6015541 | 0.76 | DCPS (0.59) | DCPSDHFRCYP2D6 | |
| SCHEMBL2165209 | 0.76 | DCPS (0.65) | DCPSDHFRCYP2D6 | |
| SCHEMBL6015552 | 0.74 | DCPS (0.54) | DCPSDHFRF2PLGPLAU | |
| SCHEMBL2165424 | 0.73 | DCPS (0.64) | DCPSDHFRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054526-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |