Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCPS | Q96C86 | 13/20 | 0.54 |
| ▸ | DHFR | P00374 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015541 | 0.93 | DCPS (0.59) | DCPSDHFRCYP2D6IKBKB | |
| SCHEMBL6015540 | 0.85 | DCPS (0.47) | DCPSDHFRCYP2D6IKBKB | |
| SCHEMBL1155228 | 0.82 | DCPS (0.74) | DCPSDHFRCYP2D6 | |
| Hydrochloric Acid SCHEMBL1154677 | 0.81 | DCPS (0.72) | DCPSDHFRCYP2D6 | |
| SCHEMBL6015543 | 0.81 | DCPS (0.80) | DCPSDHFRCYP2D6 | |
| SCHEMBL12322101 | 0.80 | IRAK4 (0.43) | DCPSDHFRIRAK4SLC6A2SLC6A4 | |
| SCHEMBL6015539 | 0.79 | CHRNB2 (0.51) | DCPSDHFRF2PLGPLAU | |
| SCHEMBL6015547 | 0.79 | CHRNB2 (0.51) | DCPSDHFRF2PLGPLAU | |
| SCHEMBL6015537 | 0.78 | HRH1 (0.43) | DCPSDHFRSLC6A2SLC6A3 | |
| SCHEMBL6015544 | 0.77 | DCPS (0.57) | DCPSDHFRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054526-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |