Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCPS | Q96C86 | 8/20 | 0.50 |
| ▸ | DHFR | P00374 | 3/20 | 0.50 |
| ▸ | QPCT | Q16769 | 3/20 | 0.42 |
| ▸ | QPCTL | Q9NXS2 | 3/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015554 | 0.93 | DCPS (0.55) | DCPSDHFRQPCTQPCTLHTR4 | |
| SCHEMBL30210995 | 0.88 | DCPS (0.61) | DCPSDHFRKCNH2 | |
| SCHEMBL6015537 | 0.80 | HRH1 (0.43) | DCPSDHFRQPCTQPCTL | |
| SCHEMBL6015543 | 0.78 | DCPS (0.80) | DCPSDHFRMCHR1 | |
| SCHEMBL13982643 | 0.77 | QPCT (0.43) | DCPSDHFRQPCTQPCTLHTR4 | |
| SCHEMBL5803519 | 0.75 | DCPS (0.40) | DCPSDHFRQPCTQPCTLHTR4 | |
| SCHEMBL6015544 | 0.74 | DCPS (0.57) | DCPSDHFR | |
| SCHEMBL25959258 | 0.74 | TLR7 (0.38) | DCPSDHFRHTR4MCHR1LRRK2 | |
| SCHEMBL15741371 | 0.72 | SRC (0.52) | DCPSDHFR | |
| SCHEMBL6015535 | 0.71 | DCPS (0.54) | DCPSDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054526-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |