Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.43 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KHK | P50053 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015554 | 0.85 | DCPS (0.55) | DCPSDHFRQPCTQPCTL | |
| SCHEMBL6015541 | 0.82 | DCPS (0.59) | DCPSDHFR | |
| SCHEMBL6015546 | 0.80 | DCPS (0.50) | DCPSDHFRQPCTQPCTL | |
| SCHEMBL6015540 | 0.80 | DCPS (0.47) | DCPSDHFR | |
| SCHEMBL6015552 | 0.78 | DCPS (0.54) | DCPSDHFRSLC6A2SLC6A3 | |
| SCHEMBL13982644 | 0.77 | HRH1 (0.43) | HRH1QPCTQPCTLHTR1ASLC6A2 | |
| SCHEMBL15284428 | 0.74 | DCPS (0.59) | DCPSDHFR | |
| SCHEMBL6015547 | 0.73 | CHRNB2 (0.51) | DCPSDHFR | |
| SCHEMBL6015539 | 0.73 | CHRNB2 (0.51) | DCPSDHFR | |
| SCHEMBL15283746 | 0.73 | DCPS (0.57) | DCPSDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054526-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |