Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.55 |
| ▸ | ERCC1 | P07992 | 5/20 | 0.49 |
| ▸ | ERCC4 | Q92889 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10192960 | 0.84 | SMN1; SMN2 (0.65) | SMN1; SMN2TAS1R3TAS1R1KMT2ANPC1 | |
| SCHEMBL6015559 | 0.82 | TAS1R3 (0.63) | SMN1; SMN2TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL701815 | 0.82 | RAB9A (0.65) | SMN1; SMN2TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL700929 | 0.81 | TAS1R3 (0.65) | SMN1; SMN2TAS1R3TAS1R1NPC1RAB9A | |
| SCHEMBL701506 | 0.80 | KDM4E (0.64) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL704725 | 0.79 | ALDH1A1 (0.56) | SMN1; SMN2TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL701487 | 0.79 | NPC1 (0.54) | SMN1; SMN2TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL704424 | 0.79 | TAS1R3 (0.57) | SMN1; SMN2TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL12164492 | 0.78 | TAS1R3 (0.56) | SMN1; SMN2TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL701749 | 0.78 | TAS1R3 (0.56) | SMN1; SMN2TAS1R3TAS1R1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054526-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |