Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | RGS12 | O14924 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | FPR1 | P21462 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14777942 | 0.81 | ALDH1A1 (0.61) | ALDH1A1LMNAHTTL3MBTL1CYP1A2 | |
| SCHEMBL6015613 | 0.78 | KMT2A (0.65) | ALDH1A1LMNAHTTL3MBTL1CYP1A2 | |
| SCHEMBL4207004 | 0.74 | SMN1; SMN2 (0.66) | ALDH1A1LMNAHTTL3MBTL1MAPT | |
| SCHEMBL4215805 | 0.72 | L3MBTL1 (0.46) | ALDH1A1LMNAHTTL3MBTL1MAPT | |
| SCHEMBL4206890 | 0.72 | SMN1; SMN2 (0.58) | ALDH1A1LMNAHTTL3MBTL1MEN1 | |
| SCHEMBL6408375 | 0.72 | ALDH1A1 (0.56) | ALDH1A1LMNAHTTL3MBTL1CYP1A2 | |
| SCHEMBL1864520 | 0.70 | HSP90AA1 (0.52) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL4212057 | 0.70 | GAA (0.49) | ALDH1A1LMNAHTTL3MBTL1MAPT | |
| SCHEMBL4215752 | 0.70 | HTT (0.67) | ALDH1A1LMNAHTTCYP1A2CYP3A4 | |
| SCHEMBL4206997 | 0.69 | ALDH1A1 (0.53) | ALDH1A1LMNAHTTL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054526-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |