Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | GLA | P06280 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 8/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | RGS12 | O14924 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | FPR1 | P21462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6406218 | 0.82 | TSHR (0.56) | ALDH1A1MAPTHPGDKDM4EGLA | |
| SCHEMBL6406516 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDKDM4EGLA | |
| SCHEMBL931408 | 0.79 | ESR1 (0.41) | ALDH1A1LMNAHTTCYP1A2CYP3A4 | |
| SCHEMBL6403612 | 0.78 | ALDH1A1 (0.61) | ALDH1A1MAPTHPGDKDM4EGLA | |
| SCHEMBL19549093 | 0.76 | SMN1; SMN2 (0.39) | ALDH1A1MAPTHPGDKDM4ELMNA | |
| SCHEMBL929707 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDKDM4EGLA | |
| SCHEMBL19549118 | 0.74 | HSD11B1 (0.54) | ALDH1A1MAPTHPGDKDM4EGLA | |
| SCHEMBL19549077 | 0.74 | HSD11B1 (0.41) | ALDH1A1MAPTKDM4ETDP1HSD17B10 | |
| SCHEMBL2988338 | 0.73 | TSHR (0.56) | ALDH1A1MAPTHPGDKDM4ELMNA | |
| SCHEMBL6015587 | 0.72 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ALDH1A1 720/4885MAPT 2111/4885HPGD 835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.