Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015561 | 0.77 | ALDH1A1 (0.42) | POLBALDH1A1GAAABL1RIN1 | |
| SCHEMBL6015562 | 0.74 | ALDH1A1 (0.40) | POLBALDH1A1GAAABL1RIN1 | |
| SCHEMBL1621745 | 0.71 | ALDH1A1 (0.50) | POLBALDH1A1GAAABL1RIN1 | |
| SCHEMBL6015575 | 0.71 | ALDH1A1 (0.39) | POLBALDH1A1GAAABL1RIN1 | |
| SCHEMBL2773009 | 0.71 | NOS1 (0.36) | POLBALDH1A1GAATDP1HPGD | |
| SCHEMBL2372149 | 0.66 | LMNA (0.34) | IDO1KMT2A | |
| SCHEMBL13757223 | 0.66 | IDO1 (0.50) | POLBALDH1A1GAAABL1RIN1 | |
| SCHEMBL6015570 | 0.66 | ABCB1 (0.57) | GAASMN1; SMN2L3MBTL1 | |
| SCHEMBL5471444 | 0.59 | IDO1 (0.37) | IDO1 | |
| SCHEMBL2745624 | 0.59 | TLR8 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054526-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |