Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015580 | 0.87 | MAPT (0.66) | MAPTL3MBTL1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6015595 | 0.77 | DAO (0.38) | MAPTL3MBTL1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL26316119 | 0.74 | L3MBTL1 (0.41) | MAPTL3MBTL1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL5513538 | 0.74 | NPC1 (0.58) | MAPTSMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL5510570 | 0.72 | MAPT (0.62) | MAPTL3MBTL1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL26316100 | 0.72 | ACHE (0.47) | MAPTL3MBTL1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6015614 | 0.70 | PDE2A (0.39) | ALDH1A1HTTRAB9ANPC1TP53 | |
| SCHEMBL22296047 | 0.67 | KDM4E (0.44) | MAPTL3MBTL1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL14777569 | 0.67 | SYK (0.40) | MAPTALDH1A1HTTRAB9AKMT2A | |
| SCHEMBL22434766 | 0.67 | ACHE (0.44) | MAPTL3MBTL1ALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054526-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |