Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 10/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.60 |
| ▸ | NPC1 | O15118 | 8/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015608 | 0.87 | MAPT (0.56) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL5510570 | 0.86 | MAPT (0.62) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL6015594 | 0.80 | MAPT (1.00) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL6015589 | 0.77 | CYP1A2 (0.52) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL1378355 | 0.74 | NPC1 (0.78) | KMT2ARAB9ANPC1LMNA | |
| Hydrochloric Acid SCHEMBL4270262 | 0.73 | NPC1 (0.77) | KMT2ARAB9ANPC1LMNA | |
| SCHEMBL11158098 | 0.70 | RAB9A (0.55) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL27945846 | 0.70 | CYP1A2 (0.59) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL6015579 | 0.69 | NPC1 (1.00) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL26316100 | 0.69 | ACHE (0.47) | MAPTALDH1A1RAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054526-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |