Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015888 | 0.90 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL6015881 | 0.88 | HPGD (0.32) | ALDH1A1TSHRL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL6015670 | 0.82 | EPHX1 (0.32) | — | |
| SCHEMBL6016011 | 0.78 | TSHR (0.32) | ALDH1A1TSHR | |
| SCHEMBL6015656 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TSHRL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL27620069 | 0.75 | TSHR (0.37) | ALDH1A1TSHRL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL6015865 | 0.69 | HPGD (0.38) | L3MBTL1 | |
| SCHEMBL5536597 | 0.68 | ALDH1A1 (0.49) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL5539416 | 0.68 | ESR1 (0.50) | ALDH1A1TSHRSMN1; SMN2MAPT | |
| SCHEMBL6015815 | 0.68 | DPP4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | disclosed |