Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620069 | 0.94 | TSHR (0.37) | ALDH1A1MAPTTSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL6015894 | 0.89 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2GAAKMT2ARAB9A | |
| SCHEMBL6015884 | 0.87 | HPGD (0.39) | ALDH1A1MAPTTSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL6015672 | 0.81 | EPHX1 (0.33) | ALDH1A1MAPTKMT2A | |
| SCHEMBL6015845 | 0.81 | KDM4E (0.31) | ALDH1A1HTTPOLB | |
| SCHEMBL6015701 | 0.79 | SMN1; SMN2 (0.42) | ALDH1A1L3MBTL1SMN1; SMN2KMT2AHDAC1 | |
| SCHEMBL6015815 | 0.78 | DPP4 (0.31) | — | |
| SCHEMBL6016013 | 0.77 | ALDH1A1 (0.37) | ALDH1A1TSHRSMN1; SMN2HTTGAA | |
| SCHEMBL6015654 | 0.76 | ALDH1A1 (0.33) | ALDH1A1MAPTTSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL6016047 | 0.75 | HTR3A (0.39) | ALDH1A1MAPTGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |