Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015656 | 0.94 | ALDH1A1 (0.39) | TSHRL3MBTL1ALDH1A1MAPTHTT | |
| SCHEMBL6015894 | 0.83 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KMT2ARAB9AGAA | |
| SCHEMBL6015672 | 0.82 | EPHX1 (0.33) | ALDH1A1MAPTKMT2A | |
| SCHEMBL6015845 | 0.82 | KDM4E (0.31) | ALDH1A1HTTKDM4E | |
| SCHEMBL6015884 | 0.81 | HPGD (0.39) | TSHRL3MBTL1ALDH1A1MAPTHTT | |
| SCHEMBL6015815 | 0.79 | DPP4 (0.31) | — | |
| SCHEMBL6016013 | 0.78 | ALDH1A1 (0.37) | TSHRALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL6016047 | 0.76 | HTR3A (0.39) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL6015654 | 0.75 | ALDH1A1 (0.33) | TSHRL3MBTL1ALDH1A1MAPTHTT | |
| SCHEMBL6015948 | 0.75 | HTR3A (0.41) | L3MBTL1ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1636005-A | Benzothiazinone and benzoxazinone compounds | KNOLL AG (DE) | 2005-07-06 | — | — | CN | claimed |
| CN-1636005-A | Benzothiazinone and benzoxazinone compounds | KNOLL AG (DE) | 2005-07-06 | — | — | CN | disclosed |