Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 11/20 | 0.40 |
| ▸ | PRKCB | P05771 | 8/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | PRKCA | P17252 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015738 | 1.00 | GSK3B (0.40) | GSK3BPRKCBCDK1CDK2RPS6KA3 | |
| SCHEMBL6087986 | 0.77 | CNR1 (0.44) | GSK3BPRKCBCDK1CDK2RPS6KA3 | |
| SCHEMBL7623790 | 0.76 | KMT2A (0.40) | KDRRAB9ANPC1HTTALDH1A1 | |
| SCHEMBL7615155 | 0.70 | PARP1 (0.49) | GSK3BPRKCBCDK1CDK2CCNB2 | |
| SCHEMBL6015844 | 0.68 | KMT2A (0.62) | RAB9ANPC1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL6015847 | 0.68 | KMT2A (0.62) | RAB9ANPC1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL6015951 | 0.68 | PARP1 (0.45) | GSK3BPRKCBCDK1CDK2CCNB2 | |
| SCHEMBL6015876 | 0.63 | RAB9A (0.49) | KDRRAB9ANPC1HTTALDH1A1 | |
| SCHEMBL6015883 | 0.63 | RAB9A (0.49) | KDRRAB9ANPC1HTTALDH1A1 | |
| SCHEMBL6090619 | 0.62 | GSK3B (0.44) | GSK3BPRKCBCDK1CDK2RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |