Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | PARP1 | P09874 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015847 | 1.00 | KMT2A (0.62) | KMT2AMEN1PARP1MAPTALDH1A1 | |
| SCHEMBL7615155 | 0.79 | PARP1 (0.49) | KMT2AMEN1PARP1MAPTSMN1; SMN2 | |
| SCHEMBL1249239 | 0.77 | KMT2A (0.66) | KMT2AMEN1PARP1MAPTALDH1A1 | |
| SCHEMBL1249238 | 0.77 | KMT2A (0.66) | KMT2AMEN1PARP1MAPTALDH1A1 | |
| SCHEMBL12892091 | 0.77 | KMT2A (0.66) | KMT2AMEN1PARP1MAPTALDH1A1 | |
| SCHEMBL6015951 | 0.77 | PARP1 (0.45) | KMT2AMEN1PARP1MAPTSMN1; SMN2 | |
| SCHEMBL8686384 | 0.74 | PARP1 (0.61) | KMT2AMEN1PARP1MAPTALDH1A1 | |
| SCHEMBL8686383 | 0.74 | PARP1 (0.61) | KMT2AMEN1PARP1MAPTALDH1A1 | |
| SCHEMBL1520957 | 0.71 | ALDH1A1 (0.64) | KMT2AMEN1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL30718481 | 0.71 | ALDH1A1 (0.64) | KMT2AMEN1ALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | disclosed |