Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015883 | 1.00 | RAB9A (0.49) | RAB9ANPC1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL6015779 | 0.77 | ALDH1A1 (0.47) | RAB9ANPC1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL6015776 | 0.77 | ALDH1A1 (0.47) | RAB9ANPC1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL6015616 | 0.76 | KDM4E (0.48) | RAB9ANPC1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL6015615 | 0.76 | KDM4E (0.48) | RAB9ANPC1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL6089323 | 0.68 | MAPT (0.32) | RAB9ANPC1HTTSMN1; SMN2MAPT | |
| SCHEMBL6089319 | 0.68 | MAPT (0.32) | RAB9ANPC1HTTSMN1; SMN2MAPT | |
| SCHEMBL8085252 | 0.68 | PIM1 (0.67) | RAB9ANPC1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL8085249 | 0.68 | PIM1 (0.67) | RAB9ANPC1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL15571574 | 0.68 | PIM1 (0.67) | RAB9ANPC1HTTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | disclosed |