Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 14/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 12/20 | 0.61 |
| ▸ | TP53BP1 | Q12888 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MBTD1 | Q05BQ5 | 7/20 | 0.54 |
| ▸ | L3MBTL4 | Q8NA19 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016066 | 0.78 | RXFP1 (0.52) | HRH3 | |
| SCHEMBL6015770 | 0.77 | L3MBTL1 (0.50) | L3MBTL1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6015752 | 0.76 | KMT2A (0.55) | L3MBTL1KMT2AKDM4E | |
| SCHEMBL6015942 | 0.75 | L3MBTL3 (0.61) | L3MBTL3L3MBTL1TP53BP1MEN1KMT2A | |
| SCHEMBL6015689 | 0.74 | HRH4 (0.43) | MEN1KMT2AHRH3KDM4EALDH1A1 | |
| SCHEMBL4489212 | 0.74 | L3MBTL3 (0.80) | L3MBTL3L3MBTL1TP53BP1MEN1KMT2A | |
| SCHEMBL6015774 | 0.73 | MAPK14 (0.42) | HRH3KDM4EALDH1A1 | |
| SCHEMBL23682962 | 0.71 | L3MBTL3 (1.00) | L3MBTL3L3MBTL1TP53BP1MEN1KMT2A | |
| SCHEMBL1085050 | 0.70 | L3MBTL3 (0.76) | L3MBTL3L3MBTL1TP53BP1MEN1KMT2A | |
| SCHEMBL23682947 | 0.70 | L3MBTL3 (1.00) | L3MBTL3L3MBTL1TP53BP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |