Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 9/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015770 | 0.95 | L3MBTL1 (0.50) | KMT2AHRH4L3MBTL1POLBKDM4E | |
| SCHEMBL6015689 | 0.81 | HRH4 (0.43) | KMT2AHRH4KDM4EHPGD | |
| SCHEMBL6016066 | 0.80 | RXFP1 (0.52) | HRH4HPGD | |
| SCHEMBL6015774 | 0.80 | MAPK14 (0.42) | HTTPOLBKDM4EHPGD | |
| SCHEMBL6015875 | 0.76 | L3MBTL3 (0.61) | KMT2AL3MBTL1KDM4E | |
| SCHEMBL6015947 | 0.74 | POLB (0.53) | KMT2AHRH4POLBHPGD | |
| SCHEMBL14818758 | 0.73 | HTT (0.84) | KMT2AHRH4L3MBTL1HTTPOLB | |
| SCHEMBL8291050 | 0.72 | KEAP1 (0.54) | KMT2AHRH4L3MBTL1HPGD | |
| SCHEMBL10722273 | 0.71 | L3MBTL1 (0.74) | KMT2AL3MBTL1HTTPOLBKDM4E | |
| SCHEMBL15966084 | 0.70 | KMT2A (0.68) | KMT2AHRH4L3MBTL1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | disclosed |