Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016049 | 0.80 | HTT (0.43) | ALDH1A1KDM4ESMN1; SMN2TSHRCYP2C19 | |
| SCHEMBL4168685 | 0.79 | GRIN1 (0.44) | SMN1; SMN2TSHR | |
| SCHEMBL6015620 | 0.78 | HTT (0.50) | POLBKDM4ESMN1; SMN2KMT2AGAA | |
| SCHEMBL6015950 | 0.73 | KMT2A (0.50) | ALDH1A1KDM4EKMT2AGAAGLA | |
| SCHEMBL2805248 | 0.72 | CNR2 (0.41) | ALDH1A1KDM4ESMN1; SMN2TSHRKMT2A | |
| SCHEMBL2559327 | 0.72 | KMT2A (0.69) | POLBALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL6015870 | 0.71 | ALDH1A1 (0.54) | POLBALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL2948314 | 0.71 | KDM4E (0.38) | ALDH1A1KDM4ESMN1; SMN2TSHRHPGD | |
| SCHEMBL24480023 | 0.70 | POLB (0.75) | POLBALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL17824289 | 0.68 | LMNA (0.66) | POLBSMN1; SMN2TSHRKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| CN-1636005-A | Benzothiazinone and benzoxazinone compounds | KNOLL AG (DE) | 2005-07-06 | — | — | CN | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |
| CN-1636005-A | Benzothiazinone and benzoxazinone compounds | KNOLL AG (DE) | 2005-07-06 | — | — | CN | disclosed |