Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | POLR1A | O95602 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015745 | 0.78 | KDM4E (0.46) | — | |
| SCHEMBL3514147 | 0.72 | NPSR1 (0.40) | — | |
| SCHEMBL6015618 | 0.70 | KMT2A (0.45) | — | |
| SCHEMBL2068928 | 0.70 | LMNA (0.42) | — | |
| SCHEMBL6016081 | 0.68 | TSHR (0.52) | — | |
| SCHEMBL6015946 | 0.66 | MAPT (0.55) | — | |
| SCHEMBL2068285 | 0.66 | KMT2A (0.43) | — | |
| SCHEMBL29143694 | 0.64 | MEN1 (0.43) | — | |
| SCHEMBL2067370 | 0.64 | POLB (0.46) | — | |
| SCHEMBL10401440 | 0.64 | CYP2D6 (0.58) | HDAC4HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |