SCHEMBL601627

SCHEMBL601627

CO[SiH](CCCC#N)OC

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL387670 0.93 TSHR (0.40) TSHRALDH1A1TDP1
SCHEMBL5682860 0.84
SCHEMBL235281 0.76 TSHR (0.44) TSHRALDH1A1TDP1
SCHEMBL399613 0.74
SCHEMBL2864684 0.73 TSHR (0.46) TSHR
SCHEMBL24180445 0.70 TSHR (0.48) TSHRALDH1A1TDP1
SCHEMBL2831289 0.70
SCHEMBL32679661 0.70 ALDH3A1 (0.33) TSHRALDH1A1TDP1
SCHEMBL914868 0.70 TSHR (0.42) TSHR
Fluoride SCHEMBL28176314 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1339727-B1 PROCESS FOR PREPARING PRIMARY AMINOORGANOSILANES GEN ELECTRIC (US) 2006-09-13 EP claimed
EP-1634885-A1 Process for preparing primary aminoorganosilanes General Electric Company (US) 2006-03-15 EP claimed
EP-1448569-A1 PROCESS FOR PREPARING BIS(SILYLORGANO)AMINES General Electric Company (US) 2004-08-25 EP claimed
EP-1339727-A1 PROCESS FOR PREPARING PRIMARY AMINOORGANOSILANES Crompton Corporation (US) 2003-09-03 EP claimed
WO-2003044027-A1 PROCESS FOR PREPARING BIS(SILYLORGANO) AMINES GENERAL ELECTRIC COMPANY (US) 2003-05-30 WO claimed
US-6417381-B1 HYDROGENATION OF CYANOORGANOSILANE USING RHODIUM, RUTHENIUM, PALLADIUM, OR PLATINUM CATALYST CROMPTON CORPORATION 2002-07-09 US claimed
WO-2002046202-A1 PROCESS FOR PREPARING PRIMARY AMINOORGANOSILANES CROMPTON CORPORATION (US) 2002-06-13 WO claimed
US-5420196-A Polyacrylate adhesion GENERAL ELECTRIC COMPANY (US) 1995-05-30 US claimed
US-5232982-A Having fillers, plasticizers, cyano-silane promoters, disilazane stabilizers, tin diketonate complex curing agents; stable, fast cure GENERAL ELECTRIC COMPANY (US) 1993-08-03 US claimed
US-5213899-A ROOM TEMPERATURE VULCANIZABLE SILICONE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1993-05-25 US claimed
US-5117024-A Hydrogenation with hydrogen gas of cyanoorganosilane in the presence of a supported cobalt catalyst DOW CORNING CORPORATION (US) 1992-05-26 US claimed
US-12098261-B2 Near-infrared absorbing material fine particle dispersion body, near-infrared absorbing body, near-infrared absorbing substance laminated body and combined structure for near infrared absorption SUMITOMO METAL MINING CO., LTD. (JP) 2024-09-24 US disclosed
CN-111699421-B Near-infrared-absorbing-material fine particle dispersion, near-infrared absorber, near-infrared-absorbing-material laminate, and near-infrared-absorbing sandwich structure 住友金属矿山株式会社 2023-03-24 CN disclosed
US-20210070961-A1 NEAR-INFRARED ABSORBING MATERIAL FINE PARTICLE DISPERSION BODY, NEAR-INFRARED ABSORBING BODY, NEAR-INFRARED ABSORBING SUBSTANCE LAMINATED BODY AND COMBINED STRUCTURE FOR NEAR INFRARED ABSORPTION SUMITOMO METAL MINING CO., LTD. (JP) 2021-03-11 US disclosed
EP-3761082-A1 NEAR INFRARED RAY ABSORPTION MATERIAL MICRO-PARTICLE DISPERSION, NEAR INFRARED RAY ABSORBER, NEAR INFRARED RAY ABSORPTION LAMINATE, COMBINED STRUCTURE FOR NEAR INFRARED RAY ABSORPTION SUMITOMO METAL MINING CO., LTD. (JP) 2021-01-06 EP disclosed
EP-0491482-A1 Room temperature vulcanizable silicone compositions having improved low modulus GENERAL ELECTRIC COMPANY (US) 1992-06-24 EP disclosed
EP-0491483-A1 Adhesion promoter system for one-component RTV silicone compositions GENERAL ELECTRIC COMPANY (US) 1992-06-24 EP disclosed
US-5117024-A Hydrogenation with hydrogen gas of cyanoorganosilane in the presence of a supported cobalt catalyst DOW CORNING CORPORATION (US) 1992-05-26 US disclosed
US-4528353-A Adhesion promoters for one-component RTV silicone compositions GENERAL ELECTRIC COMPANY (US) 1985-07-09 US disclosed
US-4483973-A Adhesion promoters for one-component RTV silicone compositions GENERAL ELECTRIC COMPANY (US) 1984-11-20 US disclosed