Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.60 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016333 | 0.84 | TACR1 (0.56) | TACR1 | |
| SCHEMBL7707342 | 0.82 | TACR1 (0.56) | TACR1 | |
| SCHEMBL6016506 | 0.76 | TACR1 (0.48) | TACR1 | |
| SCHEMBL8786855 | 0.75 | TACR1 (1.00) | TACR1 | |
| SCHEMBL6016581 | 0.74 | TACR1 (0.46) | TACR1 | |
| SCHEMBL6016399 | 0.74 | ALDH1A1 (0.49) | — | |
| SCHEMBL5966343 | 0.74 | TACR1 (0.77) | TACR1 | |
| SCHEMBL8784990 | 0.72 | TACR1 (0.81) | TACR1 | |
| SCHEMBL8785037 | 0.71 | TACR1 (0.66) | TACR1 | |
| SCHEMBL7709573 | 0.71 | TACR1 (0.55) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187815-B1 | 4-PHENYL-PYRIMIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2006-02-08 | — | — | EP | disclosed |