SCHEMBL3551870

SCHEMBL3551870

CCOC(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.44
MME P08473 2/20 0.44
ACE P12821 1/20 0.44
CPA1 P15085 1/20 0.44
ACE2 Q9BYF1 1/20 0.44
ALDH1A1 P00352 5/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
LMNA P02545 3/20 0.42
KDM4E B2RXH2 2/20 0.42
TSHR P16473 1/20 0.42
HTT P42858 1/20 0.42
GAA P10253 2/20 0.41
MGAM O43451 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
ATM Q13315 1/20 0.41
MAPK1 P28482 2/20 0.39
MAPT P10636 2/20 0.39
HSD17B10 Q99714 2/20 0.38
FAAH O00519 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL753926 1.00 TYR (0.44) TYRMMEACECPA1ACE2
SCHEMBL10513380 1.00 TYR (0.44) TYRMMEACECPA1ACE2
Hydrochloric Acid SCHEMBL28802170 0.98 TYR (0.43) TYRMMEACECPA1ACE2
Hydrochloric Acid SCHEMBL27346770 0.98 TYR (0.43) TYRMMEACECPA1ACE2
SCHEMBL11189746 0.84 METAP2 (0.46) TYRALDH1A1SMN1; SMN2LMNAHTT
SCHEMBL22751568 0.84 METAP2 (0.46) TYRALDH1A1SMN1; SMN2LMNAHTT
SCHEMBL19787736 0.84 MME (0.44) TYRMMEACECPA1ACE2
SCHEMBL6016802 0.83 SMN1; SMN2 (0.50) MMEACECPA1ACE2ALDH1A1
SCHEMBL28774200 0.83 TYR (0.42) TYRMMEACECPA1ACE2
SCHEMBL6016803 0.83 SMN1; SMN2 (0.50) MMEACECPA1ACE2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0357750-B1 URETHANE-PROTECTED AMINO ACID-N-CARBOXYANHYDRIDES BIORESEARCH INC (US) 1994-07-13 EP claimed
JP-62039552-A None JP disclosed
US-20250177383-A1 DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF DICE ALPHA, INC. 2025-06-05 US disclosed
EP-4482823-A1 DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF Dice Alpha, Inc. (US) 2025-01-01 EP disclosed
CN-119072465-A Bicyclic propyl-based IL-17A modulators and uses thereof 戴斯阿尔法公司 2024-12-03 CN disclosed
WO-2023164057-A1 DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF DICE ALPHA, INC. (US) 2023-08-31 WO disclosed
EP-2029551-B1 PYRIDINONE AND PYRIDAZINONE DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) MSD ITALIA SRL (IT) 2018-10-31 EP disclosed
US-9938239-B2 Method for preparing silodosin SANDOZ AG (CH) 2018-04-10 US disclosed
EP-2768806-B1 METHOD FOR PREPARING SILODOSIN SANDOZ AG (CH) 2017-05-31 EP disclosed
WO-2017050259-A1 PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF XW LABORATORIES INC. (KY) 2017-03-30 WO disclosed
EP-0443513-A2 Azoxy compounds KOWA COMPANY, LTD. (JP) 1991-08-28 EP disclosed
EP-0357750-A4 URETHANE-PROTECTED AMINO ACID-N-CARBOXYANHYDRIDES 1991-01-30 EP disclosed
EP-0357750-A1 URETHANE-PROTECTED AMINO ACID-N-CARBOXYANHYDRIDES. BIORESEARCH INC (US) 1990-03-14 EP disclosed
WO-1989008643-A1 URETHANE-PROTECTED AMINO ACID-N-CARBOXYANHYDRIDES BIORESEARCH, INC. (US) 1989-09-21 WO disclosed
JP-S6239552-A 2-AMINO-4'-ISOBUTYLPROPIOPHENONE ACETAL KYOWA HAKKO KOGYO CO LTD 1987-02-20 JP disclosed
US-4618710-A Preparation of optically active ketones THE REGENTS OF THE UNIVERSITY OF CALIF. (US) 1986-10-21 US disclosed
US-4496755-A Optically active 1-(6-methoxy-2-naphthyl)-2-(alkoxycarbonyl) amino-1-propanone, its derivatives and their halo analogs and the methods for their manufacture SAGAMI CHEMICAL RESEARCH CENTER (JP) 1985-01-29 US disclosed
EP-0091757-A1 Optically active 1-(6-methoxy-2-naphthyl)-2-alkoxycarbonyl)amino-1-propanone, its derivatives and their halo anlogs, and methods for their manufacture SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1983-10-19 EP disclosed
US-4367230-A ANTIANOXIC AGENTS TANABE SEIYAKU CO., LTD. (JP) 1983-01-04 US disclosed
EP-0053015-A1 1-Phenylthio-2-aminopropane derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1982-06-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250177383-A1 DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF IL17A, IL23R, IL2 TYR 2053/4885MME 4811/4885ACE 4441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.