Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3551870 | 1.00 | TYR (0.44) | TYRMMEACECPA1ACE2 | |
| SCHEMBL10513380 | 1.00 | TYR (0.44) | TYRMMEACECPA1ACE2 | |
| Hydrochloric Acid SCHEMBL28802170 | 0.98 | TYR (0.43) | TYRMMEACECPA1ACE2 | |
| Hydrochloric Acid SCHEMBL27346770 | 0.98 | TYR (0.43) | TYRMMEACECPA1ACE2 | |
| SCHEMBL11189746 | 0.84 | METAP2 (0.46) | TYRALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL22751568 | 0.84 | METAP2 (0.46) | TYRALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL19787736 | 0.84 | MME (0.44) | TYRMMEACECPA1ACE2 | |
| SCHEMBL6016802 | 0.83 | SMN1; SMN2 (0.50) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL28774200 | 0.83 | TYR (0.42) | TYRMMEACECPA1ACE2 | |
| SCHEMBL6016803 | 0.83 | SMN1; SMN2 (0.50) | MMEACECPA1ACE2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62039552-A | — | — | None | — | — | JP | disclosed |
| US-20250177383-A1 | DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. | 2025-06-05 | — | — | US | disclosed |
| EP-4482823-A1 | DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF | Dice Alpha, Inc. (US) | 2025-01-01 | — | — | EP | disclosed |
| WO-2024043313-A1 | REVERSIBLE THERMOCHROMIC COMPOSITION, MICROENCAPSULATED PIGMENT USING SAID REVERSIBLE THERMOCHROMIC COMPOSITION, WRITING TOOL, AND TOY | 三菱ケミカル株式会社 | 2024-02-29 | — | — | WO | disclosed |
| WO-2023214576-A1 | CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS | 中外製薬株式会社 | 2023-11-09 | — | — | WO | disclosed |
| WO-2023164057-A1 | DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2023-08-31 | — | — | WO | disclosed |
| US-11155559-B2 | Sulfonyl-substituted isoquinolines as inhibitors of RHO kinase and hERG potassium channel activity | CHINA RESOURCES PHARMACEUTICAL HOLDINGS COMPANY LIMITED (CN) | 2021-10-26 | — | — | US | disclosed |
| US-20200207772-A1 | ISOQUINOLINYLSULFONYL DERIVATIVE AND USE THEREOF | CHINA RESOURCES PHARMACEUTICAL HOLDINGS COMPANY LIMITED (CN) | 2020-07-02 | — | — | US | disclosed |
| EP-3656772-A1 | ISOQUINOLINYLSULFONYL DERIVATIVE AND USE THEREOF | China Resources Pharmaceutical Holdings Company Limited (CN) | 2020-05-27 | — | — | EP | disclosed |
| EP-2029551-B1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | MSD ITALIA SRL (IT) | 2018-10-31 | — | — | EP | disclosed |
| WO-2007138355-A1 | PYRROLO[1,2-A]PYRAZIN-1(2H)-ONE AND PYRROLO[1,2-D][1,2,4]TRIAZIN-1(2H)-ONE DERIVATIVES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE(PARP) | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-12-06 | — | — | WO | disclosed |
| WO-2003066624-A1 | PYRIMIDINONESULFAMOYLUREAS AS INTEGRIN LIGANDS | ABBOTT GMBH & CO. KG (DE) | 2003-08-14 | — | — | WO | disclosed |
| US-5466858-A | Ruthenium catalyst, high selectivity with a carboxylic acid | UBE INDUSTRIES, LTD. (JP) | 1995-11-14 | — | — | US | disclosed |
| EP-0443513-B1 | Azoxy compounds | KOWA CO (JP) | 1995-02-22 | — | — | EP | disclosed |
| US-5264559-A | Fungicides | KOWA COMPANY LTD. (JP) | 1993-11-23 | — | — | US | disclosed |
| EP-0443513-A2 | Azoxy compounds | KOWA COMPANY, LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| JP-S6239552-A | 2-AMINO-4'-ISOBUTYLPROPIOPHENONE ACETAL | KYOWA HAKKO KOGYO CO LTD | 1987-02-20 | — | — | JP | disclosed |
| US-4618710-A | Preparation of optically active ketones | THE REGENTS OF THE UNIVERSITY OF CALIF. (US) | 1986-10-21 | — | — | US | disclosed |
| US-4367230-A | ANTIANOXIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1983-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200207772-A1 | ISOQUINOLINYLSULFONYL DERIVATIVE AND USE THEREOF | RHOT2, ROCK2, CIT | TYR 756/4885MME 2695/4885ACE 1463/4885 |
| US-20250177383-A1 | DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF | IL17A, IL23R, IL2 | TYR 2053/4885MME 4811/4885ACE 4441/4885 |
| US-11155559-B2 | Sulfonyl-substituted isoquinolines as inhibitors of RHO kinase and hERG potassium channel activity | KCNQ2, KCNQ1, KCNH3 | TYR 682/4885MME 4020/4885ACE 3826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.