Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 3/20 | 0.44 |
| ▸ | GALR1 | P47211 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 2/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.40 |
| ▸ | SOD1 | P00441 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4837784 | 0.81 | CYP19A1 (0.49) | GALR2GALR1QPCTSMN1; SMN2TLR9 | |
| SCHEMBL5549956 | 0.80 | EGFR (0.42) | GALR1EGFRABL1BCRSRC | |
| SCHEMBL6016937 | 0.77 | QPCT (0.46) | GALR2GALR1QPCTSCN9ATLR9 | |
| SCHEMBL5549907 | 0.72 | VNN1 (0.42) | GALR2GALR1 | |
| SCHEMBL5555642 | 0.71 | GALR2 (0.42) | GALR2GALR1EGFRITK | |
| SCHEMBL1391873 | 0.70 | LMNA (0.45) | EGFRMAPTSOD1 | |
| SCHEMBL13938872 | 0.70 | MAPK14 (0.51) | — | |
| SCHEMBL3291713 | 0.68 | GALR2 (0.67) | GALR2GALR1 | |
| SCHEMBL5550957 | 0.67 | EHMT2 (0.48) | GALR2GALR1SRCMAPTSMN1; SMN2 | |
| SCHEMBL13326014 | 0.66 | GALR2 (0.67) | GALR2GALR1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7112587-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2006-09-26 | — | — | US | disclosed |