Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 3/20 | 0.67 |
| ▸ | GALR1 | P47211 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | CTSL | P07711 | 3/20 | 0.60 |
| ▸ | CTSS | P25774 | 3/20 | 0.60 |
| ▸ | CTSK | P43235 | 3/20 | 0.60 |
| ▸ | CTSB | P07858 | 1/20 | 0.60 |
| ▸ | CTSV | O60911 | 1/20 | 0.55 |
| ▸ | PLAT | P00750 | 1/20 | 0.55 |
| ▸ | CTSH | P09668 | 1/20 | 0.55 |
| ▸ | CASP14 | P31944 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | CTSZ | Q9UBR2 | 1/20 | 0.55 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13326006 | 0.85 | RAB9A (0.74) | GALR2GALR1RAB9ACTSLCTSS | |
| SCHEMBL3291713 | 0.84 | GALR2 (0.67) | GALR2GALR1CTSLCTSSCTSK | |
| SCHEMBL13326019 | 0.82 | RAB9A (0.66) | GALR2GALR1RAB9ACTSLCTSS | |
| SCHEMBL29609042 | 0.82 | NFKB1 (0.64) | RAB9AKCNH3APPMAPTSMN1; SMN2 | |
| SCHEMBL13326017 | 0.82 | NFKB1 (0.64) | RAB9AKCNH3APPMAPTSMN1; SMN2 | |
| SCHEMBL5031260 | 0.82 | RAB9A (0.62) | RAB9ACTSLCTSSCTSKCTSB | |
| SCHEMBL13326004 | 0.81 | GAA (0.74) | GALR2GALR1RAB9ACTSLCTSS | |
| SCHEMBL4829781 | 0.81 | RAB9A (0.65) | GALR2GALR1RAB9ACTSLCTSS | |
| SCHEMBL14600703 | 0.81 | RAB9A (0.75) | RAB9ACTSLCTSSCTSKCTSV | |
| SCHEMBL20938665 | 0.81 | RAB9A (0.75) | RAB9ACTSLCTSSCTSKCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718655-B2 | Trisubstituted triazine compounds, and methods for making and using the compounds, which have antitubulin activity | NEW YORK UNIVERSITY (US) | 2010-05-18 | — | — | US | disclosed |
| US-7718655-B2 | Trisubstituted triazine compounds, and methods for making and using the compounds, which have antitubulin activity | NEW YORK UNIVERSITY (US) | 2010-05-18 | — | — | US | disclosed |