Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | YES1 | P07947 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAP3K8 | P41279 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5549907 | 0.86 | VNN1 (0.42) | GBA1VNN1 | |
| SCHEMBL5554946 | 0.81 | CCNA2 (0.39) | GBA1VNN1 | |
| SCHEMBL4837957 | 0.81 | GALR1 (0.46) | HPGDMAPTMAP3K8DRD2 | |
| SCHEMBL4832751 | 0.77 | GALR2 (0.54) | GBA1DRD2 | |
| SCHEMBL6428767 | 0.77 | VNN1 (0.43) | GBA1VNN1KMT2ADRD2ACHE | |
| SCHEMBL6428015 | 0.75 | PRKCQ (0.42) | GBA1 | |
| SCHEMBL14294122 | 0.74 | GALR1 (0.49) | VNN1HPGDMAP3K8KDM4EALDH1A1 | |
| SCHEMBL14294121 | 0.73 | MAP3K8 (0.43) | VNN1MEN1KMT2AMAPTMAP3K8 | |
| SCHEMBL4841107 | 0.73 | CTSL (0.46) | VNN1HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL14293847 | 0.72 | DRD2 (0.38) | VNN1RAB9AMAP3K8DRD2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132423-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2006-11-07 | — | — | US | disclosed |