Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 12/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | CYBB | P04839 | 1/20 | 0.41 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3372422 | 1.00 | NCF1 (0.55) | NCF1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6310846 | 0.85 | ALDH1A1 (0.68) | NCF1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL17688025 | 0.84 | ALDH1A1 (0.66) | NCF1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL11261747 | 0.83 | CYP1A2 (0.58) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL30967549 | 0.83 | CYP1A2 (0.58) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL1838872 | 0.83 | ALDH1A1 (0.69) | CYP1A2CYP2C9CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL2846218 | 0.81 | CYP1A2 (0.47) | NCF1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL31172404 | 0.81 | CYP1A2 (0.47) | NCF1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL249321 | 0.80 | CYP1A2 (0.65) | CYP1A2CYP2C9CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL19991729 | 0.79 | CYP1A2 (0.62) | NCF1CYP1A2CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |