Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | NCF1 | P14598 | 6/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYBB | P04839 | 1/20 | 0.42 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17688025 | 0.98 | ALDH1A1 (0.66) | ALDH1A1CYP1A2CYP2C19CYP2C9NCF1 | |
| SCHEMBL17537502 | 0.88 | CYP1A2 (0.64) | ALDH1A1CYP1A2CYP2C19CYP2C9NCF1 | |
| SCHEMBL13531826 | 0.88 | CYP1A2 (0.64) | ALDH1A1CYP1A2CYP2C19CYP2C9NCF1 | |
| SCHEMBL13435256 | 0.88 | CYP1A2 (0.64) | ALDH1A1CYP1A2CYP2C19CYP2C9NCF1 | |
| SCHEMBL31510123 | 0.87 | CYP1A2 (0.70) | ALDH1A1CYP1A2CYP2C19CYP2C9NCF1 | |
| SCHEMBL11562109 | 0.86 | L3MBTL1 (0.59) | ALDH1A1CYP1A2CYP2C19NCF1TDP1 | |
| SCHEMBL29708563 | 0.85 | CYP1A2 (0.72) | ALDH1A1CYP1A2CYP2C19CYP2C9NCF1 | |
| SCHEMBL864648 | 0.85 | CYP1A2 (0.72) | ALDH1A1CYP1A2CYP2C19CYP2C9NCF1 | |
| SCHEMBL3372422 | 0.85 | NCF1 (0.55) | ALDH1A1CYP1A2CYP2C19CYP2C9NCF1 | |
| SCHEMBL6017004 | 0.85 | NCF1 (0.55) | ALDH1A1CYP1A2CYP2C19CYP2C9NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110778-A1 | Heterocyclic compounds as ligands of the GABAA receptor | YOHANNES DANIEL (US) | 2004-06-10 | — | — | US | claimed |
| EP-1325006-A2 | HETEROCYCLIC COMPOUNDS AS LIGANDS OF THE GABA A? RECEPTOR | NEUROGEN CORPORATION (US) | 2003-07-09 | — | — | EP | claimed |
| US-20030105081-A1 | Heterocyclic compounds as ligands of the GABAA receptor | PFIZER INC | 2003-06-05 | — | — | US | claimed |
| WO-2002012442-A2 | HETEROCYCLIC COMPOUNDS AS LIGANDS OF THE GABAA RECEPTOR | NEUROGEN CORPORATION (US) | 2002-02-14 | — | — | WO | claimed |
| EP-3044208-B1 | OXIME ESTER PHOTOINITIATORS | BASF SE (DE) | 2021-12-22 | — | — | EP | disclosed |
| US-10793555-B2 | Oxime ester photoinitiators | BASF SE (DE) | 2020-10-06 | — | — | US | disclosed |
| US-20180208583-A1 | OXIME ESTER PHOTOINITIATORS | BASF SE (DE) | 2018-07-26 | — | — | US | disclosed |
| EP-3044208-A1 | OXIME ESTER PHOTOINITIATORS | BASF SE (DE) | 2016-07-20 | — | — | EP | disclosed |
| WO-2015036910-A1 | OXIME ESTER PHOTOINITIATORS | BASF SE (DE) | 2015-03-19 | — | — | WO | disclosed |
| EP-1957457-B1 | OXIME ESTER PHOTOINITIATORS | BASF SE (DE) | 2013-02-27 | — | — | EP | disclosed |
| US-6949562-B2 | Heterocyclic compounds as ligands of the GABAA receptor | NEUROGEN CORPORATION (US) | 2005-09-27 | — | — | US | disclosed |
| US-6699959-B2 | EXHIBITS A FLOW BEHAVIOR SIMILAR TO THAT OF A LINEAR POLYCARBONATE OF COMPARABLE MOLECULAR WEIGHT OBTAINED BY THE INTERFACE POLYMERIZATION PROCESS. | BAYER AKTIENGESELLSCHAFT (DE) | 2004-03-02 | — | — | US | disclosed |
| EP-0937751-B1 | Metallized azo ether dyes and optical recording elements comprising the same | EASTMAN KODAK CO (US) | 2002-07-17 | — | — | EP | disclosed |
| US-6270943-B1 | MULTILAYER; TRANSPARENT GROOVED SUBSTRATE, RECORDING LAYER, LIGHT REFLECTING LAYER, ADHESIVE | EASTMAN KODAK COMPANY | 2001-08-07 | — | — | US | disclosed |
| EP-0937751-A1 | Metallized azo ether dyes and optical recording elements comprising the same | EASTMAN KODAK COMPANY (US) | 1999-08-25 | — | — | EP | disclosed |
| EP-0938085-A1 | Optical recording elements containing mixture of metallized azo ether and cyanine dyes | EASTMAN KODAK COMPANY (US) | 1999-08-25 | — | — | EP | disclosed |
| US-4216152-A | Process for making N-(N'-methylenepyrrolidonyl)-2-substituted anilines | GAF CORPORATION (US) | 1980-08-05 | — | — | US | disclosed |
| US-4203901-A | Process for making N-(N'-methylenepyrrolidonyl)-2-substituted anilines | GAF CORPORATION (US) | 1980-05-20 | — | — | US | disclosed |
| US-4202821-A | N-(N'-Methylenepyrrolidonyl)-2-substituted anilines | GAF CORPORATION (US) | 1980-05-13 | — | — | US | disclosed |
| US-4178168-A | Herbicidal n-(haloacetyl)-n-(n-methylene pyrrolidonyl)-2-oxyalkyleneoxyalkylanilines | GAF CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105081-A1 | Heterocyclic compounds as ligands of the GABAA receptor | GABRB1, GABRP, GABRA1 | ALDH1A1 1197/4885CYP1A2 385/4885CYP2C19 354/4885 |
| US-10793555-B2 | Oxime ester photoinitiators | NR2E3, OXER1, CBR3 | ALDH1A1 929/4885CYP1A2 64/4885CYP2C19 107/4885 |
| US-20040110778-A1 | Heterocyclic compounds as ligands of the GABAA receptor | GABRB1, GABRP, GABRA1 | ALDH1A1 1197/4885CYP1A2 385/4885CYP2C19 354/4885 |
| US-20180208583-A1 | OXIME ESTER PHOTOINITIATORS | NR2E3, OXER1, CBR3 | ALDH1A1 929/4885CYP1A2 64/4885CYP2C19 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.