Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.57 |
| ▸ | MAP2 | P11137 | 1/20 | 0.44 |
| ▸ | RHEB | Q15382 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523253 | 0.83 | RHEB (0.54) | PIN1RHEBKMT2AF7F3 | |
| SCHEMBL15625904 | 0.82 | PIN1 (0.78) | PIN1RHEBMAPK10FAAHMAPT | |
| SCHEMBL30586477 | 0.82 | PIN1 (0.78) | PIN1RHEBMAPK10FAAHMAPT | |
| SCHEMBL6017008 | 0.79 | TMPRSS4 (0.54) | PIN1KMT2AFAAHIDH1MAPT | |
| SCHEMBL4399173 | 0.77 | PIN1 (0.53) | PIN1RHEBKMT2AMAPTNPC1 | |
| SCHEMBL20305429 | 0.74 | PIN1 (1.00) | PIN1KMT2AFAAHTP53MAPT | |
| SCHEMBL3064168 | 0.73 | KMT2A (0.46) | MAP2RHEBKMT2AFAAHF7 | |
| SCHEMBL29414225 | 0.73 | KMT2A (0.46) | MAP2RHEBKMT2AFAAHF7 | |
| SCHEMBL14690377 | 0.72 | PIN1 (0.58) | PIN1MAP2RHEBMAPK10FAAH | |
| SCHEMBL20495425 | 0.72 | PIN1 (0.61) | PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |