Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30912925 | 0.84 | SMN1; SMN2 (0.50) | TMPRSS4LMNAMAPTHTTTDP1 | |
| SCHEMBL16208387 | 0.81 | THRB (0.70) | LMNAMAPTTHRBMEN1KMT2A | |
| SCHEMBL14340103 | 0.80 | KCNQ3 (0.54) | MEN1KMT2ARXFP1 | |
| SCHEMBL14516678 | 0.79 | KCNQ3 (0.51) | TMPRSS4LMNAMAPTTDP1FAAH | |
| SCHEMBL6017009 | 0.79 | PIN1 (0.57) | MAPTFAAHPIN1IDH1NPC1 | |
| SCHEMBL3588802 | 0.78 | KDR (0.53) | LMNAMAPTHTTTDP1NPC1 | |
| SCHEMBL17538665 | 0.76 | ENPP1 (0.52) | TMPRSS4LMNAMAPTTSHRHTT | |
| SCHEMBL29086861 | 0.76 | GRIK1 (0.48) | LMNAFAAHTHRBNPC1RAB9A | |
| SCHEMBL30642989 | 0.76 | GRIK1 (0.48) | LMNAFAAHTHRBNPC1RAB9A | |
| SCHEMBL28372986 | 0.76 | RAB9A (0.71) | LMNAMAPTHTTTDP1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |